A mononuclear cell is any cell that has a single round nucleus; for example, lymphocyte, monocyte, dendritic cells. These cells are a critical component of the immune system to help fight infection.

Mononuclear cells are widely used in research and clinical uses everyday such as in immunology, infectious disease, hematological malignancies, vaccine development, transplant immunology, and high-throughput screening.

HemaCare can isolate mononuclear cells from peripheral blood - Peripheral Blood Mononuclear Cells (PBMC) - and cord blood - Cord Blood Mononuclear Cells (CBMC). Mononuclear cells can be produced on demand and provided fresh or from a frozen inventory.

HemaCare has the capability to prepare and provide mononuclear cells according to your specifications:

• Specialized research donor subject recruitment
• Customized collections

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HemaCare can source disease state material from donors with autoimmune disorders, infectious diseases, or certain rare disorders (among others). Some examples of disease states include:

• Celiac Disease
• Crohn’s disease
• Lupus (SLE)
• Psoriasis
• Rheumatoid Arthritis
• Rheumatoid Factor (RF)
• HIV, HPV, HBV & HCV positive donors

If you don’t see a product you are looking for, contact us! (877) 397-3087.

Packaging and shipping specifications play an important role in maintaining the quality of your product. We package and ship all products to your specifications.

Mononuclear cells are typically packaged and shipped overnight on the day of collection. Unless instructed otherwise, mononuclear cells are packaged to maintain a temperature between 1 and 10°C or 20 and 24°C during shipment.

Temperature monitoring data tracking devices are available for use at your request.

Our healthy donor subjects for research products are screened with the same stringent regulations and requirements as donors who donate transfusable blood components.

Donors must:

• Be at least 18 years old.
• Weigh at least 140 lbs.
• Be in good health and feeling well.
• Not be pregnant.
• Meet protocol specifications, i.e. CBC lab tests.
• Be prescreened for evidence of transmissible infectious diseases (HIV, Hepatitis B, and Hepatitis C) before donation. This panel of tests is repeated with each product collection.
• Have adequate peripheral veins for apheresis.
• Complete and sign a Donor History Questionnaire developed by the AABB and accepted by the FDA and a procedure-specific consent form prior to the collection procedure. All consents and protocols have been approved by an independent biomedical review board (IRB).